60 Capsules 

• May help support the gut's healthy response to ingested histamine
• May help support a healthy immune system
• Supports the gut microbiome
• Acid-resistant capsules for targeted delivery to the gut

ProBiota HistaminX contains probiotic species that have been carefully selected to exclude those that are known to increase histamine in the gut. The histamine-friendly species included in this formula are delivered in a delayed release (acid resistant) capsule to ensure that the probiotics are delivered intact to the lower digestive tract. This formula helps to support the body's microbiome and healthy digestion, and may help support healthy metabolism of ingested histamine.

Histamine, a part of the body's biological defense system, is also found in many common dietary sources: fermented foods, fish, meat, cheese, vinegar, alcohol, and some fruits and vegetables. Other foods contain histidine, which is converted to histamine during digestion by certain bacteria in the gut. At healthy levels and in the right places, histamine is needed for a normal digestive process and sleep-wake cycle, and for a functioning immune system. On the other hand, too much histamine can cause unpleasant side effects like rashes, itching, stuffy nose, swelling, headache and gastrointestinal complaints.

Histamine is metabolized in your body via your DAO (diamine oxidase) enzymes. Due to genetic variations, some individuals have slower DAO enzymes. Your DAO enzymes can also become stressed from your environment or lifestyle. This can slow down histamine metabolism, leading to high histamine levels. DAO enzymes can be further slowed by leaky gut, alcohol, and certain drugs. Slow enzyme activity combined with high-histamine foods can cause high histamine levels in your body. This, in turn, can lead to increased levels of inflammation and histamine intolerance in a vicious cycle.

Intestinal microbes assist us in digesting foods. In the process, they may produce byproducts that either help or harm us. Some specific bugs like Salmonella typhi have long been known to irritate the intestinal tract and increase the release of histamine in immune cells. Some organisms used as probiotics (like Lactobacillus casei and Lactobacillus d. bulgaricus) may also contribute to a build up of gut histamine levels. In someone with histamine intolerance, this may lead to a rise in histamine associated complications.

A healthy microbiome is essential to support your body’s response to histamine. Gut health can also alleviate potential stress from slowed DAO enzyme activity. The probiotic strains found in ProBiota HistaminX help to lessen your DAO enzyme’s workload by excluding species known to produce histamine. This unique probiotic also supports a healthy response to histamine from food and a normal inflammatory response in the gut. By lessening your DAO enzyme’s workload, you can support the efficiency of your histamine pathway.

Key Ingredients

• Histamine-friendly probiotics: Support healthy histamine levels in your body, specifically excluding strains known to produce histamine^†
• Acid-resistant capsules: Protect probiotics from stomach acid to help deliver them intact to the gut.^†
• Inulin-Free: Does not contain inulin for those who are sensitive to prebiotics and carbohydrates.^†