Will these work with spacers and lifted suspensions?

Yes. The 50mm length is designed to accommodate wheel spacers and aftermarket suspension. Just verify your stud length before installation to ensure proper engagement.

Do I need any special tools to install these?

You'll need a lug wrench or impact socket that fits M12 hardware. Install the same way you would factory lug nuts — hand-start first, then torque to your vehicle's specification. Refer to your service manual for correct torque values.

Are these a direct swap for my factory lug nuts?

They're a direct thread-fit for M12 X 1.5 studs, but the extended 50mm length means they're built for wheels and setups that sit further out. If you're running stock wheels without spacers, factory nuts are usually the better choice.